ITS09 p18-20*
نویسنده
چکیده
The CVIS (Co-operative VehicleInfrastructure Systems) project was launched in February 2006 to develop a platform which would allow vehicles to communicate and co-operate directly with other nearby vehicles and with roadside infrastructure. The first deliverable of this major endeavour, involving some 60 partners, is the publication of the CVIS high level architecture which, unlike many of today’s information systems, will not become outdated when new technologies arrive. A report by Andreas Schmid and Zeljko Jeftic
منابع مشابه
Cleavage of Bax to p18 Bax accelerates stress-induced apoptosis, and a cathepsin-like protease may rapidly degrade p18 Bax.
Bax is cleaved by calpain at aspartate 33 (Asp33) to yield p18 Bax during stress-induced apoptosis. To assess the role of p18 Bax in apoptosis, an ecdysone-inducible expression system was generated. Similar levels of wild-type (WT) and noncleavable Asp33Ala (Asp-->Ala) Bax are induced in 293 cells while expression of N-terminal-deleted p18 (Delta1-33) Bax remains low (20% of full-length p21 Bax...
متن کاملThe influence of age at the beginning of Montanera period on meat characteristics and fat quality of outdoor Iberian pigs.
A total of 120 Iberian pigs of the Lampiña line that grew under outdoor conditions were used to study the effect of the age at the beginning of Montanera period (AM) on meat characteristics and fatty acid (FA) profile of subcutaneous fat. AM period is a free-range fattening phase from November to February in which pigs ate mainly acorns and grass. There were two treatments with two AM (20 pigs ...
متن کاملThe Haploinsufficient Tumor Suppressor p18 Upregulates p53 via Interactions with ATM/ATR
p18 was first identified as a factor associated with a macromolecular tRNA synthetase complex. Here we describe the mouse p18 loss-of-function phenotype and a role for p18 in the DNA damage response. Inactivation of both p18 alleles caused embryonic lethality, while heterozygous mice showed high susceptibility to spontaneous tumors. p18 was induced and translocated to the nucleus in response to...
متن کاملSilencing of the p18 gene by promoter hypermethylation in the Reed-Sternberg cells in Hodgkin Lymphomas
p18 is a cyclin-dependent kinase inhibitor that interferes with the Rb-kinase activity of CDK6/CDK4. Disruption of p18 in mice impairs B-cell terminal differentiation and confers increased susceptibility to tumor development; however, alterations of p18 in human tumors have rarely been described. We used a tissue-microarray approach to analyze p18 expression in 316 Hodgkin Lymphomas (HL). Nearl...
متن کاملSynergistic effect of oncogenic RET and loss of p18 on medullary thyroid carcinoma development.
Activating mutations in the RET proto-oncogene are associated with both familial and sporadic medullary thyroid carcinoma (MTC) development; however, the genetic mechanisms underlying MTC tumorigenesis remain largely unknown. Recently, we have identified somatic inactivating mutations in the cell cycle inhibitor gene P18 in human MTC, which coincided with activating RET mutations, suggesting a ...
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تاریخ انتشار 2007